WARNING:
JavaScript is turned OFF. None of the links on this concept map will
work until it is reactivated.
If you need help turning JavaScript On, click here.
This Concept Map, created with IHMC CmapTools, has information related to: Antifungal Drugs, Antifungal Drugs ???? Echocandins, Antifungal Drugs ???? Griseofulvin, Broad Spectrum ???? Voriconazole, Azoles ???? Interfere with Ergosterol. biosynthesis. NB inhibit Cyp450, Amphotericin B - IV-administered, used for systemic infections. It binds to ergosterol in cell wall causing leakage of material. Amp B is toxic to renal tubules. Nystatin is an ointment for oral candidiasis. Natamycin is topical and used for eye infections. e.g Amphotericin B, Flucytosine ???? Interferes with protein synthesis., Antifungal Drugs ???? Imidazoles, Polyenes ???? Amphotericin B - IV-administered, used for systemic infections. It binds to ergosterol in cell wall causing leakage of material. Amp B is toxic to renal tubules. Nystatin is an ointment for oral candidiasis. Natamycin is topical and used for eye infections., Antifungal Drugs ???? Azoles, Triazoles ???? Fluconazole, Imidazoles ???? Clotrimazole, Interfere with Ergosterol. biosynthesis. NB inhibit Cyp450 e.g Broad Spectrum, Antifungal Drugs ???? Polyenes, Non-competitive inhibitors of glucan synthase (cell wall) e.g Anidulafungin, Interfere with Ergosterol. biosynthesis. NB inhibit Cyp450 e.g Triazoles, Antifungal Drugs ???? Other antifungal agents, Triazoles ???? Itraconazole, Echocandins ???? Non-competitive inhibitors of glucan synthase (cell wall), Griseofulvin ???? Binds to keratin precursor making cells resistant to fungal invasion., Non-competitive inhibitors of glucan synthase (cell wall) e.g Micafungin